Molecular Basis of Ligand-Dependent Regulation of NadR, the Transcriptional Repressor of Meningococcal Virulence Factor NadA.

Neisseria adhesin A (NadA) is present on the meningococcal surface and contributes to adhesion to and invasion of human cells. NadA is also one of three recombinant antigens in the recently-approved Bexsero vaccine, which protects against serogroup B meningococcus. The amount of NadA on the bacteria...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Alessia Liguori, Enrico Malito, Paola Lo Surdo, Luca Fagnocchi, Francesca Cantini, Andreas F Haag, Sébastien Brier, Mariagrazia Pizza, Isabel Delany, Matthew J Bottomley
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Public Library of Science (PLoS) 2016-04-01
Schriftenreihe:	PLoS Pathogens
Online-Zugang:	http://europepmc.org/articles/PMC4841544?pdf=render
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