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PD-1/PD-L1 and coronary heart disease: a mendelian randomization study

IntroductionIt has been found that programmed cell death protein-1 (PD-1) or its ligand PD-L1 may play an important role in the onset and progression of coronary heart disease (CHD). Thus, we conducted this mendelian randomization analysis (MR) to estimate the causal relationship between PD-1/PD-L1...

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Autori principali: Liangjia Zeng, Yinglan Liang, Ruoyun Zhou, Wenting Yang, Kexin Chen, Baixin He, Yuqing Qiu, Linglong Liu, Deyang Zhou, Zhaolin Xiao, Haowen Liang, Binghua Zhang, Renyu Li, Lihong Yu, Min Yi, Xiaozhen Lin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2024-10-01
Serie:Frontiers in Cardiovascular Medicine
Soggetti:
Mendelian randomization (MR)
coronary heart disease (CHD)
PD-1
PD-L1
GSEA
Accesso online:https://www.frontiersin.org/articles/10.3389/fcvm.2024.1424770/full
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