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Andrographolide Inhibits Epstein–Barr Virus Lytic Reactivation in EBV-Positive Cancer Cell Lines through the Modulation of Epigenetic-Related Proteins

Reactivation of Epstein–Barr virus (EBV) is associated with EBV-associated malignancies and is considered to be a benefit target for treatment. Andrographolide is claimed to have antiviral and anti-tumor activities. Therefore, this study aimed to investigate the effect of andrographolide on the inhi...

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Principais autores: Praphatson Malat, Tipaya Ekalaksananan, Chukkris Heawchaiyaphum, Supawadee Suebsasana, Sittiruk Roytrakul, Yodying Yingchutrakul, Chamsai Pientong
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2022-07-01
Series:Molecules
Assuntos:
andrographolide
Epstein–Barr virus
lytic reactivation
BZLF1
histone modifications
Acceso en liña:https://www.mdpi.com/1420-3049/27/14/4666
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