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Multiple myeloma primary cells show a highly rearranged unbalanced genome with amplifications and homozygous deletions irrespective of the presence of immunoglobulin-related chromosome translocations

Background and Objectives Multiple myeloma (MM) is a malignant plasma cell neoplasia in which genetic studies have shown that genomic changes may affect almost all chromosomes, as shown by fluorescence in situ hybridization (FISH) and comparative genomic hybridization (CGH). Our objective was the ge...

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Váldodahkkit: Cristina Largo, Borja Saéz, Sara Alvarez, Javier Suela, Bibiana Ferreira, David Blesa, Felipe Prosper, M. Jose Calasanz, Juan C. Cigudosa
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Ferrata Storti Foundation 2007-06-01
Ráidu:Haematologica
Liŋkkat:https://haematologica.org/article/view/4473
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