The cJUN NH2-terminal kinase (JNK) signaling pathway promotes genome stability and prevents tumor initiation

Breast cancer is the most commonly diagnosed malignancy in women. Analysis of breast cancer genomic DNA indicates frequent loss-of-function mutations in components of the cJUN NH2-terminal kinase (JNK) signaling pathway. Since JNK signaling can promote cell proliferation by activating the AP1 transc...

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Detalles Bibliográficos

Autores principales:	Nomeda Girnius, Yvonne JK Edwards, David S Garlick, Roger J Davis
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	eLife Sciences Publications Ltd 2018-06-01
Colección:	eLife
Materias:	stress-activated MAPK JNK breast cancer
Acceso en línea:	https://elifesciences.org/articles/36389
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