Advances in post-translational and epigenetic modification of hyperuricemia-to-gout progression: mechanisms and therapeutic targets

Hyperuricemia (HUA) and gout are endocrine disorders resulting from abnormal uric acid (UA) metabolism, with gout typically developing secondary to HUA and being associated with an exacerbated inflammatory response. Epigenetic modifications and post-translational modifications (PTMs) may contribute...

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Auteurs principaux:	Wei Fu, Xiangman Xu, Xinze Li, Qian Guo, Peng Liu, Lulu Chen, Wenfei Cheng, Zikuan Zhang, Zilong Chen, Chuanxin Liu
Format:	Artigo
Langue:	Inglês
Publié:	Frontiers Media S.A. 2026-05-01
Collection:	Frontiers in Cell and Developmental Biology
Sujets:	epigenetic modifications gout hyperuricemia post-translational modifications therapeutic targets
Accès en ligne:	https://www.frontiersin.org/articles/10.3389/fcell.2026.1749194/full
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