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Curcumin Suppressed Activation of Dendritic Cells via JAK/STAT/SOCS Signal in Mice with Experimental Colitis

Dendritic cells (DCs) play a pivotal role as initiators in the pathogenesis of inflammatory bowel disease and are regulated by the JAK/STAT/SOCS signaling pathway. As a potent anti-inflammatory compound, curcumin represents a viable treatment alternative or adjunctive therapy in the management of ch...

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Principais autores: Hai-mei Zhao, Rong Xu, Xiao-ying Huang, Shao-min Cheng, Min-fang Huang, Hai-yang Yue, Xin Wang, Yong Zou, Ai-ping Lu, Duanyong Liu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016-11-01
coleção:Frontiers in Pharmacology
Assuntos:
Curcumin
dendritic cell
costimulatory molecules
experimental colitis
JAK/STAT/SOCS signal
Acesso em linha:http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00455/full
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