Surface immunogenic protein from Streptococcus agalactiae and Fissurella latimarginata hemocyanin are TLR4 ligands and activate MyD88- and TRIF dependent signaling pathways

The development of vaccine adjuvants is of interest for the management of chronic diseases, cancer, and future pandemics. Therefore, the role of Toll-like receptors (TLRs) in the effects of vaccine adjuvants has been investigated. TLR4 ligand-based adjuvants are the most frequently used adjuvants fo...

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Hlavní autoři:	Diego A. Díaz-Dinamarca, Michelle L. Salazar, Daniel F. Escobar, Byron N. Castillo, Bastián Valdebenito, Pablo Díaz, Augusto Manubens, Fabián Salazar, Mayarling F. Troncoso, Sergio Lavandero, Janepsy Díaz, María Inés Becker, Abel E. Vásquez
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2023-09-01
Edice:	Frontiers in Immunology
Témata:	protein-based adjuvants (PBAs) TLR4 agonist MyD88 TRIF antigen-presenting cells vaccines
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1186188/full
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