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Transcriptional profiles of pulmonary artery endothelial cells in pulmonary hypertension

Abstract Pulmonary arterial hypertension (PAH) is characterized by endothelial cell (EC) dysfunction. There are no data from living patients to inform whether differential gene expression of pulmonary artery ECs (PAECs) can discern disease subtypes, progression and pathogenesis. We aimed to further...

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Autores principales: Navneet Singh, Carsten Eickhoff, Augusto Garcia-Agundez, Paul Bertone, Sunita S. Paudel, Dhananjay T. Tambe, Leslie A. Litzky, Katherine Cox-Flaherty, James R. Klinger, Sean F. Monaghan, Christopher J. Mullin, Mandy Pereira, Thomas Walsh, Mary Whittenhall, Troy Stevens, Elizabeth O. Harrington, Corey E. Ventetuolo
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Portfolio 2023-12-01
Colección:Scientific Reports
Acceso en línea:https://doi.org/10.1038/s41598-023-48077-6
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