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Novel Modulators of Proteostasis: RNAi Screen of Chromosome I in a Heat Stress Paradigm in C. elegans

Proteostasis is of vital importance for cellular function and it is challenged upon exposure to acute or chronic insults during neurodegeneration and aging. The proteostasis network is relevant for the maintenance of proteome integrity and mainly comprises molecular chaperones and two degradation pa...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Andreas Kern, Natalie Spang, Heike Huesmann, Christian Behl
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2018-05-01
Schriftenreihe:Cells
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Online-Zugang:http://www.mdpi.com/2073-4409/7/6/49
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