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Evolution of SIV toward RANTES resistance in macaques rapidly progressing to AIDS upon coinfection with HHV-6A

<p>Abstract</p> <p>Background</p> <p>Progression to AIDS is often associated with the evolution of HIV-1 toward increased virulence and/or pathogenicity. Evidence suggests that a virulence factor for HIV-1 is resistance to CCR5-binding chemokines, most notably RANTES, which are believed to play a ro...

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Bibliografiske detaljer
Principais autores: Gallo Robert C, Markham Phillip D, Vanpouille Christophe, Lisco Andrea, Grivel Jean-Charles, Biancotto Angélique, Margolis Leonid B, Lusso Paolo
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2009-07-01
Serier:Retrovirology
Online adgang:http://www.retrovirology.com/content/6/1/61
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