Identification of salvianolic acid A as an ADP receptor-selective and Gq/IP3 pathway-mediated anti-platelet component in Qishen Yiqi

Abstract Background Antiplatelet therapy is crucial for preventing and treating cardio-cerebrovascular diseases. However, adverse events related to thrombosis or bleeding have been reported in instances of treatment with glycoprotein IIb/IIIa antagonists. It is anticipated that developing new select...

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Detalhes bibliográficos

Principais autores:	Wenli Dang, Liping Chen, Qinhua Shang, Tiechan Zhao, Lianying Chang, Taiyi Wang, Ming Lyu, Xiaoxuan Tian, Hao Guo, Shuang He, Jingyang Hu, Peng Zhang, Yan Zhu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-10-01
coleção:	Chinese Medicine
Assuntos:	Antiplatelet therapy Platelet activation Thrombosis G-protein coupled receptors Salvianolic acid A Qishen Yiqi dripping pill
Acesso em linha:	https://doi.org/10.1186/s13020-025-01188-w
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