Predicting intracranial hypertension as a secondary insult using the pathological peptidome of brain injured patients

Abstract Intracranial hypertension (IHT) is a common secondary insult that worsens morbidity and death after acute brain injury from traumatic and hemorrhagic events. Suspicion of IHT is determined with a combination of neurological examination and imaging but is often hampered by sedation and limit...

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Autors principals:	Kelly E. Platfoot, Alexander Satoski, Anil K. Roy, Alex B. Valadka, Andrew K. Ottens
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2026-04-01
Col·lecció:	Scientific Reports
Matèries:	Biomarker Intracranial hypertension Intracranial pressure Peptidome Secondary sequelae Stroke
Accés en línia:	https://doi.org/10.1038/s41598-026-46313-3
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