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circRNA‐SORE/UBQLN1/GPX4 Mediates the Acquisition of Sorafenib Resistance in Hepatocellular Carcinoma Through Inhibition of Ferroptosis

ABSTRACT The clinical performance of targeted therapies for treating hepatocellular carcinoma (HCC) is significantly limited by the frequent emergence of drug resistance, ultimately resulting in therapeutic failure and poor prognosis. While the precise mechanisms underlying this resistance are not f...

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Principais autores: Lin Ji, Yeling Ruan, Meng Tong, Tianyi Chen, Jingwei Cai, Zhengtao Ye, Xiujun Cai, Junjie Xu
Formato: Artigo
Idioma:Inglês
Publicado: Wiley 2025-12-01
Series:MedComm
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Acceso en liña:https://doi.org/10.1002/mco2.70488
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