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Identification of two mutation sites in spike and envelope proteins mediating optimal cellular infection of porcine epidemic diarrhea virus from different pathways

Abstract Entry of the α-coronavirus porcine epidemic diarrhea virus (PEDV) requires specific proteases to activate spike (S) protein for the membrane fusion of the virion to the host cell following receptor binding. Herein, PEDV isolate 85-7 could proliferate and induce cell–cell fusion in a trypsin...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Min Sun, Jiale Ma, Zeyanqiu Yu, Zihao Pan, Chengping Lu, Huochun Yao
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BMC 2017-08-01
Cyfres:Veterinary Research
Mynediad Ar-lein:http://link.springer.com/article/10.1186/s13567-017-0449-y
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