Desmoglein 2 and desmocollin 2 depletions promote malignancy through distinct mechanisms in triple-negative and luminal breast cancer

Abstract Background Aberrant expressions of desmoglein 2 (Dsg2) and desmocollin 2(Dsc2), the two most widely distributed desmosomal cadherins, have been found to play various roles in cancer in a context-dependent manner. Their specific roles on breast cancer (BC) and the potential mechanisms remain...

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Hlavní autoři:	Ji-Yuan Han, Na Che, Jing Mo, Dan-Fang Zhang, Xiao-Hui Liang, Xue-Yi Dong, Xiu-Lan Zhao, Bao-Cun Sun
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2024-04-01
Edice:	BMC Cancer
Témata:	Desmoglein 2 (Dsg2) Desmocollin 2 (Dsc2) Breast cancer ERK AKT β-catenin
On-line přístup:	https://doi.org/10.1186/s12885-024-12229-2
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