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Betacellulin-induced beta cell proliferation and regeneration is mediated by activation of ErbB-1 and ErbB-2 receptors.

<h4>Background</h4>Betacellulin (BTC), a member of the epidermal growth factor family, is known to play an important role in regulating growth and differentiation of pancreatic beta cells. Growth-promoting actions of BTC are mediated by epidermal growth factor receptors (ErbBs), namely ErbB-1, ErbB-...

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Hlavní autoři: Yoon Sin Oh, Seungjin Shin, Youn-Jung Lee, Eung Hwi Kim, Hee-Sook Jun
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2011-01-01
Edice:PLoS ONE
On-line přístup:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0023894&type=printable
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