Human granzyme B regulatory B cells prevent effector CD4+CD25- T cell proliferation through a mechanism dependent from lymphotoxin alpha

IntroductionHuman Granzyme B (GZMB) regulatory B cells (Bregs) have suppressive properties on CD4+ effector T cells by a mechanism partially dependent on GZMB. Moreover, these cells may be easily induced in vitro making them interesting for cell therapy.MethodsWe characterized this population of in...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Nicolas Sailliet, Hoa-Le Mai, Amandine Dupuy, Gaëlle Tilly, Cynthia Fourgeux, Martin Braud, Magali Giral, Jean-Michel Robert, Nicolas Degauque, Richard Danger, Jeremie Poschmann, Sophie Brouard
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2023-07-01
Edice:	Frontiers in Immunology
Témata:	regulatory B cell regulation single cell RNAseq tolerance GZMB LTA
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1183714/full
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!