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miRNA-206-3p alleviates LPS-induced acute lung injury via inhibiting inflammation and pyroptosis through modulating TLR4/NF-κB/NLRP3 pathway

Abstract Acute lung injury (ALI) is life-threatening. MicroRNAs (miRNAs) are often abnormally expressed in inflammatory diseases and are closely associated with ALI. This study investigates whether miRNA-206-3p attenuates pyroptosis in ALI and elucidates the underlying molecular mechanisms. ALI mous...

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Wedi'i Gadw mewn:
Prif Awduron: Mengchi Chen, Jingfeng Zhang, Hongyuan Huang, Zichen Wang, Yong Gao, Jianghua Liu
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Portfolio 2024-05-01
Cyfres:Scientific Reports
Pynciau:
ALI
miRNA-206-3p
Pyroptosis
Inflammation pathway
NLRP3
Mynediad Ar-lein:https://doi.org/10.1038/s41598-024-62733-5
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