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Altered expressions of CGRP, SULT1A1, HMGB1, and HIF-1α in the trigeminal ganglion in medication overuse headache in female rats

Abstract Background/Aim Medication-overuse headache (MOH) is a female-predominant secondary headache generally associated with nonsteroidal anti-inflammatory drug overuse and chronification of migraine. MOH is associated with elevated serum levels of inflammatory and nociceptive molecules and intest...

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Autori principali: Elif Gulcicek Abbasoglu Topa, Doga Vuralli, Duygu Deniz Usta, Aysen Calikusu, Zeynep Yigman, Hayrunnisa Bolay
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2025-10-01
Serie:The Journal of Headache and Pain
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Accesso online:https://doi.org/10.1186/s10194-025-02191-0
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