Human primary skeletal muscle cells express glutamate receptor GluR3, are activated by glutamate, and are affected by autoimmune GluR3B antibodies of epilepsy patients

BackgroundGlutamate is the major excitatory neurotransmitter in the nervous system, common in neuromuscular junctions, and with abnormally reduced levels in several muscle diseases. Glutamate receptor AMPA GluR3, encoded by the GRIA3 gene, has important neurophysiological roles in regulation of neur...

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Bibliografische Detailangaben

Hauptverfasser:	Mia Levite, Nili Ilouz, Avi Harazi, Hadassa Goldberg-Stern, Eithan Galun, Stella Mitrani-Rosenbaum
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2025-12-01
Schriftenreihe:	Frontiers in Physiology
Schlagworte:	human skeletal muscle glutamate glutamate receptor GluR3 GluR3B antibodies epilepsy
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fphys.2025.1636766/full
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