Tetra-Primer ARMS PCR Optimization for Detection of IVS-II-I (G-A) and FSC 8/9 InsG Mutations in β-Thalassemia Major Patients in Isfahan Population

Background: β -thalassemia, a monogenic autosomal recessive disorder, is prevalent in Middle East, particularly in Iran. In Iran, near to 20 mutations in the β-globin gene are introduced as common mutations with varying incidence frequencies in each city. Therefore, detection and screening for coupl...

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Главные авторы:	Samaneh Hajihoseini, Majid Motovali-Bashi, Mohammad Amin Honardoost, Nader Alerasool
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Tehran University of Medical Sciences 2015-03-01
Серии:	Iranian Journal of Public Health
Предметы:	FSC-8/9 mutation IVSII-I mutation Tetra primer amplification refractory mutation system (T-ARMS) method β-thalassemia
Online-ссылка:	https://ijph.tums.ac.ir/index.php/ijph/article/view/3637
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