Integration of intragraft transcriptomics and urinary cytokines identifies CXCL10 and FasL signature in subclinical acute rejection

Abstract Subclinical acute rejection (SCAR) in kidney transplantation, defined by histologic lesions without clinical dysfunction, remains a major cause of allograft injury and is currently detectable only by invasive protocol biopsies. We conducted a multicenter study in which transcriptomic profil...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Sharon Natasha Cox, Samantha Chiurlia, Emanuela Pasculli, Luigi Biancone, Davide Diena, Vincenzo Cantaluppi, Andrea Airoldi, Ilaria Gandolfini, Umberto Maggiore, Nicola Bossini, Michele Rossini, Graziano Pesole, Francesco Paolo Schena, Italian SCAR Study Group
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2026-02-01
Edice:	Scientific Reports
Témata:	Kidney transplantation Subclinical acute rejection CXCL10 FasL Kidney biopsy Renal inflammation
On-line přístup:	https://doi.org/10.1038/s41598-026-35923-6
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!