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Environmental influences on antibody-enhanced dengue disease outcomes

Because an enriched environment (EE) enhances T-cell activity and T-lymphocytes contribute to immunopathogenesis during heterologous dengue virus (DENV) infections, we hypothesised that an EE increases dengue severity. To compare single serotype (SS) and antibody-enhanced disease (AED) infections re...

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Autores principales: Daniel Guerreiro Diniz, César Augusto Raiol Fôro, Maíra C Pereira Turiel, Marcia CK Sosthenes, Sâmia Demachki, Giovanni Freitas Gomes, Carla M Damasceno Rego, Marina Cutrim Magalhães, Brunno Gomes Pinho, Juliana Pastana Ramos, Samir M Moraes Casseb, Maysa de Vasconcelos Brito, Eliana Vieira Pinto da Silva, Marcio Roberto Teixeira Nunes, José Antonio Picanço Diniz, Colm Cunningham, Victor Hugh Perry, Pedro F Costa Vasconcelos, Cristovam W Picanço Diniz
Formato: Artigo
Lenguaje:Inglês
Publicado: Fundação Oswaldo Cruz (FIOCRUZ) 2012-12-01
Colección:Memorias do Instituto Oswaldo Cruz
Materias:
experimental dengue infection
enriched environment
antibody-enhanced dengue disease
serial dengue infection
T-lymphocytes
Acceso en línea:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762012000800010&lng=en&tlng=en
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