JaponiconeA induces apoptosis of bortezomib-sensitive and -resistant myeloma cells in vitro and in vivo by targeting IKKβ

Objective: Multiple myeloma (MM) remains incurable with high rates of relapse. New therapeutic drugs are therefore urgently needed to improve the prognosis. JaponiconeA (JA), a natural product isolated from Inula japonica Thunb, has shown good anti-MM potential. A comprehensive study should therefor...

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Autori principali:	Zilu Zhang, Chenjing Ye, Jia Liu, Wenbin Xu, Chao Wu, Qing Yu, Xiaoguang Xu, Xinyi Zeng, Huizi Jin, Yingli Wu, Hua Yan
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	China Anti-Cancer Association 2022-05-01
Serie:	Cancer Biology & Medicine
Soggetti:	multiple myeloma nf-κb japoniconea bortezomib drug resistance
Accesso online:	https://www.cancerbiomed.org/content/19/5/651
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