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Absolute requirement of cholesterol binding for Hedgehog gradient formation in Drosophila

Summary How morphogen gradients are shaped is a major question in developmental biology, but remains poorly understood. Hedgehog (Hh) is a locally secreted ligand that reaches cells at a distance and acts as a morphogen to pattern the Drosophila wing and the vertebrate neural tube. The proper patter...

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Bibliografische gegevens
Hoofdauteurs: Antoine Ducuing, Bertrand Mollereau, Jeffrey D. Axelrod, Stephane Vincent
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Company of Biologists 2013-05-01
Reeks:Biology Open
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Online toegang:http://bio.biologists.org/content/2/6/596
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