Breast cancer stem cells generate immune-suppressive T regulatory cells by secreting TGFβ to evade immune-elimination

Abstract Cancer stem cells (CSCs), being the primary contributors in tumor initiation, metastasis, and relapse, ought to have seminal roles in evasion of immune surveillance. Tumor-promoting CD4+CD25+FOXP3+ T-regulatory cells (Tregs) have been described to abolish host defense mechanisms by impeding...

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Principais autores:	Sumon Mukherjee, Sourio Chakraborty, Udit Basak, Subhadip Pati, Apratim Dutta, Saikat Dutta, Dia Roy, Shruti Banerjee, Arpan Ray, Gaurisankar Sa, Tanya Das
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Springer 2023-12-01
סדרה:	Discover Oncology
נושאים:	Anti-tumor immunity Cancer stem cells Metastasis Microenvironment Relapse Stemness markers
גישה מקוונת:	https://doi.org/10.1007/s12672-023-00787-z
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!