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Nutritional control of body size through FoxO-Ultraspiracle mediated ecdysone biosynthesis

Despite their fundamental importance for body size regulation, the mechanisms that stop growth are poorly understood. In Drosophila melanogaster, growth ceases in response to a peak of the molting hormone ecdysone that coincides with a nutrition-dependent checkpoint, critical weight. Previous studie...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Takashi Koyama, Marisa A Rodrigues, Alekos Athanasiadis, Alexander W Shingleton, Christen K Mirth
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications Ltd 2014-11-01
Schriftenreihe:eLife
Schlagworte:
ecdysone
nutrition-dependent signaling
insulin/insulin-like growth factor
target of rapamycin
critical weight
body size
Online-Zugang:https://elifesciences.org/articles/03091
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