Interactions Between Pseudomonas Immunotoxins and the Plasma Membrane: Implications for CAT-8015 Immunotoxin Therapy

Acute Lymphoblastic Leukemia (ALL) remains the most frequent cause of cancer-related mortality in children and novel therapies are needed for the treatment of relapsed/refractory childhood ALL. One approach is the targeting of ALL blasts with the Pseudomonas immunotoxin CAT-8015. Although CAT-8015 h...

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Bibliografski detalji

Glavni autori:	Monika Bokori-Brown, Jeremy Metz, Peter G. Petrov, Francis Mussai, Carmela De Santo, Neil J. Smart, Sarah Saunders, Bridget Knight, Ira Pastan, Richard W. Titball, C. Peter Winlove
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2018-11-01
Serija:	Frontiers in Oncology
Teme:	immunotoxin cancer treatment pediatric acute lymphoblastic leukemia CAT-8015 Moxetumomab pasudotox red blood cells
Online pristup:	https://www.frontiersin.org/article/10.3389/fonc.2018.00553/full
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