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Investigation of mRNA expression levels of DNA damage response genes in Merkel Cell Polyomavirus-positive Merkel Cell Carcinoma: a pilot study

Abstract Merkel Cell Polyomavirus (MCPyV) is recognized as the major aetiological agent of Merkel Cell Carcinoma (MCC), an aggressive skin tumor. MCPyV-mediated oncogenesis is strictly dependent on viral integration and the expression of a truncated form of the Large T Antigen (LT). Moreover, like o...

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Bibliografski detalji
Glavni autori: Sara Passerini, Matteo Fracella, Amedeo Ferlosio, Ugo Moens, Carolina Scagnolari, Guido Antonelli, Marco Ciotti, Valeria Pietropaolo
Format: Artigo
Jezik:Inglês
Izdano: Springer 2025-05-01
Serija:Discover Oncology
Teme:
Online pristup:https://doi.org/10.1007/s12672-025-02651-8
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