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Protein restriction during lactation causes transgenerational metabolic dysfunction in adult rat offspring

IntroductionProtein restriction during lactation can induce metabolic dysfunctions and has a huge impact on the offspring’s phenotype later in its life. We tested whether the effects of a maternal low-protein diet (LP) in rats can be transmitted to the F2 generation and increase their vulnerability...

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Principais autores: Rodrigo Vargas, Isabela Peixoto Martins, Camila Cristina Ianoni Matiusso, Raiana Aparecida Casagrande, Camila Benan Zara, Anna Carolina Huppes de Souza, William Pereira Horst, Taina Cristine Sieklicki, Tania Cristina Alexandrino Becker, Naiara Cristina Lucredi, Jurandir Fernando Comar, Ananda Malta, Paulo Cezar de Freitas Mathias
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2023-01-01
coleção:Frontiers in Nutrition
Assuntos:
metabolic programming
maternal malnutrition
steatosis
thrifty phenotype hypothesis
metabolism
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fnut.2022.1062116/full
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