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The neurovascular and inflammatory signatures of the degenerating intervertebral disc

Objective: Inflammatory cytokine production and de novo neurovascularization have been identified in painful, degenerated intervertebral discs (IVDs). However, the progression of these key pathoanatomical features, including the cascade of inflammatory cytokines and the infiltration of vessels and n...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: RE Walk, KS Broz, L Jing, RS Potter, CE Gonzalez, AT Beeve, EL Scheller, MC Gupta, LA Setton, SY Tang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Forum Multimedia Publishing LLC 2025-12-01
Schriftenreihe:European Cells & Materials
Schlagworte:
intervertebral disc degeneration
inflammatory cytokines
intradiscal vascularization
innervation
low back pain pathoanatomy
Online-Zugang:https://www.ecmjournal.org/journal/ECM/path/vol054/10.22203/eCM.v054a05
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