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Modeling and Simulating Asymmetrical Conductance Changes in Gramicidin Pores

Gramicidin A is a small and well characterized peptide that forms an ion channel in lipid membranes. An important feature of gramicidin A (gA) pore is that its conductance is affected by the electric charges near the its entrance. This property has led to the application of gramicidin A as a biochem...

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Main Authors: Xu Shixin, Chen Minxin, Majd Sheereen, Yue Xingye, Liu Chun
Format: Artigo
Language:Inglês
Published: De Gruyter 2014-01-01
Series:Computational and Mathematical Biophysics
Subjects:
gramicidin
conductance change
finite element method
poisson-nernst-planck (pnp) equation
ion channels
Online Access:https://doi.org/10.2478/mlbmb-2014-0003
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