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Community assembly modeling of the microbiome within Barrett’s esophagus and esophageal adenocarcinoma

Abstract Computational modeling of somatic evolution, a process shaped by ecology and impacting both host cells and microbial communities in the human body, can capture important dynamics driving carcinogenesis. Here we considered models for esophageal adenocarcinoma (EAC), a cancer that has dramati...

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Kaydedildi:
Asıl Yazarlar: Caitlin Guccione, Igor Sfiligoi, Antonio Gonzalez, Justin P. Shaffer, Mariya Kazachkova, Yuhan Weng, Daniel McDonald, Shailja C. Shah, Samuel S. Minot, Thomas G. Paulson, William M. Grady, Ludmil B. Alexandrov, Rob Knight, Kit Curtius
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMC 2026-02-01
Seri Bilgileri:BMC Genomics
Konular:
Esophageal adenocarcinoma
Cancer microbiome
Mathematical modeling
Community assembly
Barrett’s esophagus
Helicobacter pylori
Online Erişim:https://doi.org/10.1186/s12864-026-12545-w
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