Associations of Alzheimer’s disease risk variants with gene expression, amyloidosis, tauopathy, and neurodegeneration

Abstract Background Genome-wide association studies have identified more than 30 Alzheimer’s disease (AD) risk genes, although the detailed mechanism through which all these genes are associated with AD pathogenesis remains unknown. We comprehensively evaluate the roles of the variants in top 30 non...

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Autors principals:	Meng-Shan Tan, Yu-Xiang Yang, Wei Xu, Hui-Fu Wang, Lin Tan, Chuan-Tao Zuo, Qiang Dong, Lan Tan, John Suckling, Jin-Tai Yu, Alzheimer’s Disease Neuroimaging Initiative
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2021-01-01
Col·lecció:	Alzheimer’s Research & Therapy
Matèries:	Alzheimer disease Amyloid Tau Neurodegeneration Risk variants Gene expression
Accés en línia:	https://doi.org/10.1186/s13195-020-00755-7
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