Chicoric acid targets PYGL to normalize glycogenolysis-driven glycolysis to suppress non-small cell lung cancer

Abstract Background Chicoric acid (CA), a bioactive natural compound found in Chicory and Echinacea purpurea, exhibits antiinflammatory, antioxidant, and apoptosis-inducing properties. However, its therapeutic potential and underlying mechanisms in non-small cell lung cancer (NSCLC) remain unclear....

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Hlavní autoři:	Xingfa Huo, Helei Hou, Chuantao Zhang, Xueqin Duan, Hongwei Lan, Yufeng Li, Na Zhou, Xiaochun Zhang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2026-04-01
Edice:	Cellular & Molecular Biology Letters
Témata:	Chicoric acid PYGL LDHA Metabolic reprogramming NSCLC
On-line přístup:	https://doi.org/10.1186/s11658-026-00930-y
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