Solid-Phase Synthesized Copolymers for the Assembly of pH-Sensitive Micelles Suitable for Drug Delivery Applications

Diblock copolymers of polyhistidine are known for their self-assembly into micelles and their pH-dependent disassembly due to the amphiphilic character of the copolymer and the unsaturated imidazole groups that undergo a hydrophobic-to-hydrophilic transition in an acidic pH. This property has been l...

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Principais autores:	Razvan Ghiarasim, Crina Elena Tiron, Adrian Tiron, Mihail-Gabriel Dimofte, Mariana Pinteala, Alexandru Rotaru
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2022-05-01
coleção:	Nanomaterials
Assuntos:	polyhistidine copolymers micelles doxorubicin tumor cells release studies
Acesso em linha:	https://www.mdpi.com/2079-4991/12/11/1798
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