Large-scale EM data reveals myelinated axonal changes and altered connectivity in the corpus callosum of an autism mouse model

IntroductionAutism spectrum disorder (ASD) encompasses a diverse range of neurodevelopmental disorders with complex etiologies, including genetic, environmental, and neuroanatomical factors. While the exact mechanisms underlying ASD remain unclear, structural abnormalities in the brain offer valuabl...

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Detalhes bibliográficos

Principais autores:	Guoqiang Zhao, Ao Cheng, Jiahao Shi, Peiyao Shi, Jun Guo, Chunying Yin, Hafsh Khan, Jiachi Chen, Pengcheng Wang, Jiao Chen, Ruobing Zhang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2025-04-01
coleção:	Frontiers in Neuroinformatics
Assuntos:	Shank3b autism spectrum disorder corpus callosum serial scanning electron microscopy myelinated axons
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fninf.2025.1563799/full
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