Combined bacterial translocation and cholestasis aggravates liver injury by activation pyroptosis in obstructive jaundice

This study explores the mechanism by which obstructive jaundice (OJ) induces liver damage through pyroptosis. We induced OJ in rats via bile duct ligation and assessed liver damage using serum biochemical markers and histological analysis of liver tissue. Pyroptosis was investigated through immunofl...

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מידע ביבליוגרפי

Principais autores:	Xin Shen, Xin Zhang, Kaiyu Li, Guangming Huang, Xinyu Li, Yunlong Hou, Xin Ge
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Elsevier 2024-08-01
סדרה:	Heliyon
נושאים:	Obstructive jaundice Intestinal bacterial translocation Pyroptosis Inflammasome Liver injury
גישה מקוונת:	http://www.sciencedirect.com/science/article/pii/S2405844024118245
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