Aberrant activation of five embryonic stem cell-specific genes robustly predicts a high risk of relapse in breast cancers

Abstract Background In breast cancer, as in all cancers, genetic and epigenetic deregulations can result in out-of-context expressions of a set of normally silent tissue-specific genes. The activation of some of these genes in various cancers empowers tumours cells with new properties and drives enh...

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Autori principali:	Emmanuelle Jacquet, Florent Chuffart, Anne-Laure Vitte, Eleni Nika, Mireille Mousseau, Saadi Khochbin, Sophie Rousseaux, Ekaterina Bourova-Flin
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2023-08-01
Serie:	BMC Genomics
Soggetti:	Cancer/testis antigens Breast cancer Ectopic expression Survival analysis Prognosis biomarkers
Accesso online:	https://doi.org/10.1186/s12864-023-09571-3
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