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AKR1C3 promotes progression and mediates therapeutic resistance by inducing epithelial-mesenchymal transition and angiogenesis in small cell lung cancer

Objective: Small cell lung cancer (SCLC) is a high-grade neuroendocrine tumor characterized by initial sensitivity to chemotherapy, followed by the development of drug resistance. The underlying mechanisms of resistance in SCLC have not been fully elucidated. Aldo-keto reductase family 1 member C3 (...

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Hlavní autoři: Wenting Liu, Guoli Li, Dingzhi Huang, Tingting Qin
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2024-09-01
Edice:Translational Oncology
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On-line přístup:http://www.sciencedirect.com/science/article/pii/S1936523324001542
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