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Selenium speciation-dependent cancer radiosensitization by induction of G2/M cell cycle arrest and apoptosis

Introduction: Radiation therapy has Q6long been a routine and effective treatment for non-small cell lung cancer (NSCLC), but the radioresistance and side effects have limited its application. In recent years, the superiority showed by trace element selenium in tumor radiotherapy sensitization has r...

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Principais autores: Shiqing Nie, Xin He, Zhiting Sun, Yan Zhang, Ting Liu, Tianfeng Chen, Jianfu Zhao
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2023-03-01
Serier:Frontiers in Bioengineering and Biotechnology
Fag:
selenium
non-small cell lung cancer
radiosensitivity
cell cycle
apoptosis
ROS
Online adgang:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1168827/full
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