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Emerging in vitro models to study Merkel cell carcinoma pathobiology

Merkel cell carcinoma (MCC) is a rare but highly aggressive skin neoplasm, caused in approximately 80% of cases by the genomic integration of Merkel cell polyomavirus (MCPyV) and the expression of the viral small T antigen (sT) and large T antigen (LT) oncoproteins. Virus-negative tumors exhibit ext...

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Bibliografiske detaljer
Principais autores: Chiara Mazziotta, John Charles Rotondo
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2025-10-01
Serier:Frontiers in Cell and Developmental Biology
Fag:
Online adgang:https://www.frontiersin.org/articles/10.3389/fcell.2025.1691110/full
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