Increased Mesenchymal Stem Cell Functionalization in Three-Dimensional Manufacturing Settings for Enhanced Therapeutic Applications

Mesenchymal stem/stromal cell (MSC) exist within their in vivo niches as part of heterogeneous cell populations, exhibiting variable stemness potential and supportive functionalities. Conventional extensive 2D in vitro MSC expansion, aimed at obtaining clinically relevant therapeutic cell numbers, r...

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Bibliografische Detailangaben

Hauptverfasser:	Dimitrios Kouroupis, Diego Correa
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2021-02-01
Schriftenreihe:	Frontiers in Bioengineering and Biotechnology
Schlagworte:	MSC functionalization MSC spheroids MSC therapeutic properties MSC anti-inflammatory properties mesenchymal stem cell manufacturing
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fbioe.2021.621748/full
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