TMEM106B Puncta Is Increased in Multiple Sclerosis Plaques, and Reduced Protein in Mice Results in Delayed Lipid Clearance Following CNS Injury

During inflammatory, demyelinating diseases such as multiple sclerosis (MS), inflammation and axonal damage are prevalent early in the course. Axonal damage includes swelling, defects in transport, and failure to clear damaged intracellular proteins, all of which affect recovery and compromise neuro...

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Bibliografische Detailangaben

Hauptverfasser:	Bridget Shafit-Zagardo, Simone Sidoli, James E. Goldman, Juwen C. DuBois, John R. Corboy, Stephen M. Strittmatter, Hillary Guzik, Ukuemi Edema, Anita G. Arackal, Yair M. Botbol, Emilio Merheb, Rashed M. Nagra, Sarah Graff
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2023-06-01
Schriftenreihe:	Cells
Schlagworte:	multiple sclerosis (MS) TMEM106B myelin oligodendrocyte glycoprotein (MOG)-induced EAE demyelination lipids
Online-Zugang:	https://www.mdpi.com/2073-4409/12/13/1734
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