Differential LRRK2 Signalling and Gene Expression in WT-LRRK2 and G2019S-LRRK2 Mouse Microglia Treated with Zymosan and MLi2
Mutations in the leucine-rich repeat kinase 2 (<i>LRRK2</i>) gene cause autosomal dominant Parkinson’s disease (PD), with the most common causative mutation being the <i>LRRK2</i> p.G2019S within the kinase domain. LRRK2 protein is highly expressed in the human brain and also in the periphery, and h...
Sábháilte in:
| Príomhchruthaitheoirí: | , , , , , , , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe / Cruthaithe: |
MDPI AG
2023-12-01
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| Sraith: | Cells |
| Ábhair: | |
| Rochtain ar líne: | https://www.mdpi.com/2073-4409/13/1/53 |
| Clibeanna: |
Níl clibeanna ann, Bí ar an gcéad duine le clib a chur leis an taifead seo!
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