Effects of PCSK9 inhibitor evolocumab on preventing early neurological deterioration in acute ischemic stroke patients with or without large artery atherosclerosis: a subgroup analysis of a randomized trial

Abstract Background Our previous study has demonstrated the preventive effects of proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor on early neurological deterioration (END) in patients with acute non-cardiogenic ischemic stroke. Here, we performed a post hoc subgroup analysis to inves...

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Hauptverfasser:	Jiahui Liu, Ying Li, Wen Tian, Hua Cao, Xidan Li, Liyuan Cheng, Xiaofei Ji, Jing Liu
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2025-10-01
Schriftenreihe:	BMC Neurology
Schlagworte:	Acute ischemic stroke Early neurological deterioration PCSK9 inhibitor Evolocumab Large artery atherosclerosis Inflammation
Online-Zugang:	https://doi.org/10.1186/s12883-025-04434-8
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