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Polystyrene micro- and nanoplastics in a colitis mouse model – effects on biodistribution, macrophage polarization, and gut microbiome

Abstract The increasing prevalence of inflammatory bowel disease (IBD) and rising pollution from micro- and nanoplastic (MNP) particles has prompted investigations on their potential interconnection. To elucidate the complex relationship between IBD and exposure to MNPs, we induced colitis in mice u...

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Wedi'i Gadw mewn:
Prif Awduron: Verena Kopatz, Ulrike Resch, Kristina Draganic, Angela Horvath, Janette Pfneissl, Julijan Kabiljo, Bernadette Mödl, Gerald Timelthaler, Julia Wallner, Zeynab Mirzaei, Saule Beratlyte, Michaela Schlederer, Stefan Sarbu, Simina Laslau, Oldamur Hollóczki, Martin Raigel, Elisabeth S. Gruber, Joachim Widder, Iris Kufferath, Marion Pollheimer, Wolfgang Wadsak, George Sarau, Silke Christiansen, Nikola Zlatkov Kolev, Marcus Krueger, Robert Eferl, Gerda Egger, Vanessa Stadlbauer, Verena Pichler, Lukas Kenner
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: SpringerOpen 2025-12-01
Cyfres:Microplastics and Nanoplastics
Pynciau:
Micro- and nanoplastic
Polystyrene
Colitis mouse model
Proteomics
Gut microbiome
Mynediad Ar-lein:https://doi.org/10.1186/s43591-025-00160-7
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