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Ptch1 is essential for cochlear marginal cell differentiation and stria vascularis formation

Summary: A common cause of deafness in humans is dysregulation of the endocochlear potential generated by the stria vascularis (SV). Thus, proper formation of the SV is critical for hearing. Using single-cell transcriptomics and a series of Shh signaling mutants, we discovered that the Shh receptor...

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Bibliografski detalji
Glavni autori: Tianli Qin, Karl Kam Hei So, Chi-Chung Hui, Mai Har Sham
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2024-04-01
Serija:Cell Reports
Teme:
Online pristup:http://www.sciencedirect.com/science/article/pii/S221112472400411X
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