Highly Parallelized, Multicolor Optogenetic Recordings of Cellular Activity for Therapeutic Discovery Applications in Ion Channels and Disease-Associated Excitable Cells

Optogenetic assays provide a flexible, scalable, and information rich approach to probe compound effects for ion channel drug targets in both heterologous expression systems and associated disease relevant cell types. Despite the potential utility and growing adoption of optogenetics, there remains...

Descrizione completa

Dettagli Bibliografici

Autori principali:	Gabriel B. Borja, Hongkang Zhang, Benjamin N. Harwood, Jane Jacques, Jennifer Grooms, Romina O. Chantre, Dawei Zhang, Adam Barnett, Christopher A. Werley, Yang Lu, Steven F. Nagle, Owen B. McManus, Graham T. Dempsey
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2022-07-01
Serie:	Frontiers in Molecular Neuroscience
Soggetti:	optogenetics optopatch high-throughput screening ion channels voltage-gated sodium channels pain
Accesso online:	https://www.frontiersin.org/articles/10.3389/fnmol.2022.896320/full
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!